The selective reversible FAAH inhibitor, SSR411298, restores the development of maladaptive behaviors to acute and chronic stress in rodents
Deletion of the vesicular monoamine transporter 1 (vmat1/slc18a1) gene affects dopamine signaling
A two-hit story: Seizures and genetic mutation interaction sets phenotype severity in SCN1A epilepsies
Striatal cholinergic interneurons regulate cognitive and affective dysfunction in partially dopamine‐depleted mice
Inhibition of hematopoietic cell kinase dysregulates microglial function and accelerates early stage Alzheimer's disease-like neuropathology
Spared cognitive and behavioral functions prior to epilepsy onset in a rat model of subcortical band heteropia
Dorsolateral septum somatostatin interneurons gate mobility to calibrate context-specific behavioral fear responses
Posted January 20, 2020.
Dopaminergic signalling is necessary, but not sufficient for cued fear memory destabilisation
Walking activity and dispersal on deltamethrin- and spinosad-treated grains by the maize weevil Sitophilus zeamais
Rapeseed oil fortified with micronutrients improves cognitive alterations associated with metabolic syndrome
Endothelium-Derived Semaphorin 3G Regulates Hippocampal Synaptic Structure and Plasticity via Neuropilin-2/PlexinA4
Experience of behavior on mice
Memory traces are believed to be ensembles of cells used to store memories. To visualize memory traces, we created a transgenic line that allows for the comparison between cells activated during encoding and expression of a memory.
Neurocognitive deficits arising from anesthetic exposure have recently been debated, while studies have shown that the phosphorylation of cyclic AMP response element-binding protein (CREB) in the hippocampus is critical for long-term memory.
Null mutations in the gene encoding the major myelin protein of the central nervous system, proteolipid protein 1 (PLP1), cause an X-linked form of spastic paraplegia (SPG2) associated with axonal degeneration. While motor symptoms are the best known manifestations of this condition, its somatosensory disturbances have been described but poorly characterized.
Insulin resistance leads to memory impairment. Cinnamon (CN) improves peripheral insulin resistance but its effects in the brain are not known. Changes in behavior, insulin signaling and Alzheimer-associated mRNA expression in the brain were measured in male Wistar rats