Acute Adverse Effects of Metallic Nanomaterials onCardiac and Behavioral Changes in Daphnia Magna

Acute Adverse Effects of Metallic Nanomaterials onCardiac and Behavioral Changes in Daphnia Magna

AbstractNanomaterials are widely believed to induce toxic effects on organisms by evoking oxidative stress. Inthis study, we evaluated the toxic effects of nanomaterials on cardiac and behavioral changes in Daphniamagna under varying exposure conditions. Titanium dioxide nanoparticles (TiO2 NPs), silvernanoparticles (AgNPs), and silver nitrate (AgNO3) were selected for the acute toxicity tests. The adverseeffects of the substances on the neonates including heart rate, swimming speed, and oxidative stress,were measured. The heart rate level decreased as the concentration of NPs and silver ions (Ag+)increased. The average swimming speed was measured to be approximately 15 mm/min for the controlgroup. The swimming speed generally increased for longer exposure to both NPs, although it reached aplateau at the lowest concentration of AgNPs. A similar but less clear trend was observed for Ag+. For allsubstances, the overall swimming speed exhibited no correlation or weak negative correlations with theexposure concentration. The oxidative stress levels increased after exposure compared to the controlgroup. We conclude that aquatic nanotoxicity tests should consider multilevel physicochemical,physiological, and behavioral parameters.

 

Link to the publication :

https://assets.researchsquare.com/files/rs-208731/v1/0fae6790-e641-4c9c-b4d5-3383736ddb59.pdf