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Parkinsonism Driven by Antipsychotics Originates from Do...

Highlights •D2R signaling directs the striatal dopamine/acetylcholine balance •D2R signaling controls the in vitro “pause” of striatal cholinergic interneurons •Antipsychotic-induced catalepsy depends on D2R blockade on cholinergic interneurons •Acetylcholine signaling on medium spiny neurons induces catalepsy

2016-07-01