MicroZebraLab - Zebrafish Cardiology and Physiology

PUBLICATIONS

A multi-endpoint in vivo larval zebrafish (Danio rerio)...

A multi-endpoint in vivo larval zebrafish (Danio rerio) model for the assessment of integrated cardiovascular function

2014-01-01

Using Zebrafish for Investigating the Molecular Mechanis...

Using Zebrafish for Investigating the Molecular Mechanisms of Drug-Induced Cardiotoxicity

2018-09-27

Characterization of Endothelial Cilia Distribution Durin...

Characterization of Endothelial Cilia Distribution During Cerebral-Vascular Development in Zebrafish (Danio rerio)

2018-09-20

Developmental neurotoxicity and immunotoxicity induced b...

Developmental neurotoxicity and immunotoxicity induced by graphene oxide in zebrafish embryos

2018-12-13

Reduced aggrecan expression affects cardiac outflow trac...

https://www.sciencedirect.com/science/article/pii/S0167527317336379

2017-09-24

A novel method for automated tracking and quantification...

Highlights Custom-made economic imaging setup for distraction-free behavioural recording. ImageJ based algorithm for fast and automated tracking of Zebrafish without plugins. Mathematical workflow for extraction of behavioural endpoints. New representation for spatio-temporal nature of choice-based behaviours.

2011-01-01

Zebrafish as a new model for phenotype-based screening o...

The zebrafish-based assay is a widely used animal model system for cardiovascular research. In this study, we investigated the cardiac defects caused by terfenadine and tested the pharmacological response of digoxin to zebrafish with cardiac defects.

2014-07-04

Reversal of pentylenetetrazole-altered swimming and neur...

Extensive ethnopharmaceutical documentation is available on plants with demonstrated psychoactivity in humans (for review (Raetsch 2005)). Even though there is a huge need for new molecules in mental health, this reservoir of knowledge remains greatly untapped. One of the main reasons is probably the lack of a good in vivo system allowing testing of psychoactive efficacy of complex mixtures of unknown composition. Ethnobotanical reports on a specific plant often differ on plant species/subspecies/harvest but also on mode of preparation and administration which all generate a number of imponderable parameters. Therefore, it is necessary to establish a system which would be capable of circumventing those problems. Ideally, the proposed system has to be flexible and sensitive enough to allow rapid and systematic screening of a big number of complex mixtures like crude plants extracts. In such a system, first pass screening could be done with minimally processed extracts like preparations made from dried powdered parts of a plant of interest. Subsequently, gradually refined mixtures could be tested the same way to eventually isolate the active compound(s).

2011-01-01

Experimental Models of Anxiety for Drug Discovery and Br...

Experience of behavior on mice

2011-01-01

Adverse effects of parental zinc deficiency on metal hom...

http://www.sciencedirect.com/science/article/pii/S0955286316302200

2017-02-25