An open system for automatic home-cage behavioral analysis and its application to male and female mouse models of Huntington's disease
Published: 01-13-2013 In Publication
► New software for automatic video-based classification of mouse home-cage behavior. ► Software available under open-source license, allowing free modification by users. ► Motor deficits and circadian disruptions detected in male and female R6/2 mice. ► Characteristic behavioral signatures defined based on multiple facets of behaviors. ► Behavioral signatures distinguished male R6/2 mice from WT as early as 5 weeks.